Many of us have been doing this a long time, some of us are new to this fun game.
Here are my rules to a successful convention (these are to be done every 24 hours):
5 Hours of Sleep: I'm not kidding here. You must sleep at least once a day for a minimum of 5 hours. You're a night owl? Awesome! Sleep during the day.
4 Scheduled Events: Look, don't over do yourself. Try not to book back to back games. Many games do sell out the first day of event registration, many of those sold out events are not full due to people over scheduling themselves. Do you have extra time? Great! Use those generics and go to that one game you missed out on and see if there is an extra slot. Please be on time though. It sucks to hold up a whole group just because you didn't plan correctly. You're a night owl? Awesome, make sure to bring your generics to the 50 player "Are You A Werewolf?" and Magic drafts that are running all night long.
3 Meals. You NEED breakfast, You NEED lunch, You NEED dinner. No really. The amount of calories you are burning running around to all these events, getting through the exhibit hall, trying to catch that one thing that you just heard about. You need to eat. It will effect your time at your event if your stomach is growling the entire time. Night owl eh? There are several 24 hour food places (yes, they will be full) but White Castle is still open, and technically that's food (no you can't walk through the Drive Thru, yes it's been done, no it's never successful).
2 Showers. What??? No really, take one when you wake up to wake up, and take one before dinner. Change your clothes completely. Get refreshed, you never know, you might wind up in a game after dinner with the people at the other table. You might venture to a bar and get a bit out of the normal drunk, it happens. You will avoid the dreaded con crud, it's been my secret for many years. So, you are still a night owl? This still applies, get up, take a shower, before breakfast, get a shower. If anything it's relaxing.
1 Trip through the Exhibit Hall.. No really, you are going to miss that one thing you were looking for the first through fourth time. You didn't know you were looking for it. If there is something you want, bring money. Sometimes, the universe gets all wonky and cards don't work for a moment. While all the other folks are trying, you can go to the cash only line and get right on your way. On Sunday, some exhibitors really love your cash. You may indeed have some bargaining power if you have the cash on hand. I will warn you, ATM's run out of money regularly, they are all stocked each morning and the PNC in the Hyatt usually has enough money, that's a really long run for that ultimate thing you just found that only takes cash though. Night owl? You're gonna have a tough time getting into the exhibit hall. Open from Thursday - Saturday 10 am to 6 pm and Sunday 10 am to 4 pm. Make sure to get your sleep though.
That's pretty much it. If you want to add or subtract from this, please do so! Keep well!